MUCORMYCOSIS: An Overview

Mucormycosis 

Mucormycosis also known as zyomycosis. This is a serious fungal infection but it is very rare. Affects only immunocompromised patient 
The agent is mucomycetes 

Transmission
Aerosol
Cutaneous
Percutaneous 

AFFECTS
Diabetic patients especially patients with diabetic keto acidosis 
Also affects people who has taken steroids and broad spectrum antibiotics 
And also affects people with other comorbidities

TYPES  
Rhino cerebral
Pulmonary
Gastrointestinal 
Disseminated
Cutaneous
Most common is Rhino cerebral 

SYMPTOMS 
Pain
Decreased sensation over half the face
Black discoloration
STAIN USED IN MICROSCOPE 
Koh smear 
Lactophenol cotton blue 

CULTURE 
Subouraud dextrose agar at 30 c

DIAGNOSTICS 
Biopsy and culture 
     This should reach lab within 2 hours
CT non contract: mucosal thickening 
MRI: black turbinate sign
CBC : check neutropenia 

TREATMENT
Surgical debridement + toxic antifungal therapy can be given
Amphotericin B injection 
Posaconazole 
Isavuconazole 

MORTALITY: 50%

NOTE
Mucormycosis is not black fungus 
Dematecious fungi is known as black fungus 

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